Icotinib Hydrochloride

CAS No. 1204313-51-8

Icotinib Hydrochloride ( BPI-2009H )

Catalog No. M17189 CAS No. 1204313-51-8

Icotinib Hydrochloride is the hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of EGFR, with potential antineoplastic activity.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 50 Get Quote
10MG 72 Get Quote
25MG 129 Get Quote
50MG 215 Get Quote
100MG 320 Get Quote
200MG 474 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Icotinib Hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Icotinib Hydrochloride is the hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of EGFR, with potential antineoplastic activity.
  • Description
    Icotinib Hydrochloride is the hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of EGFR, with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, has been upregulated in a variety of cancer cell types.
  • Synonyms
    BPI-2009H
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    EGFR; EGFR mutants
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1204313-51-8
  • Formula Weight
    427.88
  • Molecular Formula
    C22H22ClN3O4
  • Purity
    98%
  • Solubility
    DMSO : 25 mg/mL. 58.43 mM;
  • SMILES
    C#Cc1cc(ccc1)Nc1ncnc2cc3OCCOCCOCCOc3cc12.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tan F, et al. Lung Y. 2012 May;76(2):177-82.
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